Research record
Overview
Compound name: GHRP-6
Alternative names: Growth Hormone–Releasing Peptide-6
Compound classification: Synthetic peptide; growth hormone secretagogue
Brief factual description:
GHRP-6 is a synthetic hexapeptide designed to stimulate endogenous growth hormone (GH) release by activating the ghrelin (growth hormone secretagogue) receptor. It is one of the earliest and most studied members of the GHRP class.
Mechanism of Action
Primary biological targets: Growth hormone secretagogue receptor (GHS-R1a / ghrelin receptor)
Affected systems: Endocrine, metabolic
Receptor selectivity: High affinity for GHS-R1a
Downstream signaling effects:
Stimulation of pulsatile GH release from the pituitary
Activation of appetite-related signaling via ghrelin pathways
Modulation of IGF-1 levels secondary to GH elevation




