Research record
Overview
Compound name: PT-141
Alternative names: Bremelanotide
Compound classification: Synthetic peptide; melanocortin receptor agonist
Brief factual description:
PT-141 is a synthetic peptide derived from Melanotan II and engineered to selectively target central melanocortin pathways involved in sexual desire and arousal rather than skin pigmentation.
Mechanism of Action
Primary biological targets: Melanocortin-4 receptors (MC4R)
Affected systems: Neurological, endocrine
Receptor selectivity: High selectivity for MC4R compared to Melanotan II
Downstream signaling effects:
Activation of central nervous system pathways involved in sexual desire and arousal without reliance on peripheral vasodilation mechanisms.
