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AICAR research peptide vial

Metabolic Research

AICAR

Explore AICAR research compound online, published research information. Explore its mechanism as an AMPK activator and metabolic research applications.

Catalogue record
OP-901
Intended use
Research use only
Independent COA on this site
Not available
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Research record

Overview

Compound name: AICAR

Alternative names: AICA riboside; 5-Aminoimidazole-4-carboxamide ribonucleotide (intracellular active form)

Compound classification: Small-molecule nucleoside analog; AMPK activator

Brief factual description:

AICAR is a synthetic nucleoside analog that is metabolized intracellularly to ZMP, an AMP analog. It is widely used in research to activate AMP-activated protein kinase (AMPK), a central regulator of cellular energy balance.

Mechanism of Action

Primary biological targets: AMP-activated protein kinase (AMPK)

Affected systems: Metabolic, muscular, cardiovascular, cellular energy regulation

Receptor selectivity: Enzyme signaling modulation rather than receptor binding

Downstream signaling effects:

Activation of AMPK via accumulation of ZMP

Increased glucose uptake and fatty acid oxidation

Inhibition of anabolic, ATP-consuming pathways

External sources

References published with this record

  1. Source 1: nature.com
  2. Source 2: cell.com
  3. Source 3: pubchem.ncbi.nlm.nih.gov
  4. Source 4: wada-ama.org

Frequently asked questions

What this record can—and cannot—confirm

Is AICAR approved for human use?

AICAR is supplied strictly for in-vitro laboratory and research use only, not for human consumption or therapeutic use. Regulatory treatment varies by jurisdiction.

How is the purity of AICAR verified?

No independent report for this specific product was available in the public migration source. Request batch-specific documentation from the authorised reseller before relying on a purity claim.

Where can I buy AICAR?

Through an OnlinePeptides authorized reseller. Verify any reseller at onlinepeptides.com/verify-reseller/ before purchasing.

Metabolic Research

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