Research record
Overview
Compound name: AOD-9604
Alternative names: None (distinct synthetic compound)
Compound classification: Synthetic peptide; modified growth hormone–derived analog
Brief factual description:
AOD-9604 is a synthetic peptide analog developed from the lipolytic region of human growth hormone (hGH), specifically inspired by amino acids 176–191. It is not sequence-identical to native hGH Fragment 176–191 and was engineered to selectively influence fat metabolism without activating the growth-promoting or IGF-1–mediated effects associated with full-length hGH.
Mechanism of Action
Primary biological targets: Adipocyte lipid metabolism pathways
Affected systems: Metabolic, adipose tissue
Receptor selectivity:
Does not significantly activate classical growth hormone receptors
Downstream signaling effects:
Stimulation of lipolysis (breakdown of stored triglycerides)
Inhibition of lipogenesis (formation of new fat stores)
Minimal activation of GH/IGF-1 growth pathways compared to full-length hGH




